Controlled Products Regulations (SOR/88-66)

Regulations are current to 2013-05-26 and last amended on 2010-02-23. Previous Versions

Poisonous Substances as Defined by the Transportation of Dangerous Goods Regulations

50. A pure substance or tested mixture falls into Subdivision B of Division 1 of Class D — Poisonous and Infectious Material if it is included in Packing Group III of Division 1 of Class 6 in Part III of the Transportation of Dangerous Goods Regulations.

Untested Mixtures

51. An untested mixture falls into Subdivision B of Division 1 of Class D — Poisonous and Infectious Material if it contains a product, material or substance that meets any of the criteria applicable to a pure substance or tested mixture referred to in section 49 or 50 and is present at a concentration of one per cent or more.

Division 2: Materials Causing Other Toxic Effects

Subdivision A: Very Toxic Material

Pure Substances and Tested Mixtures

Chronic Toxic Effects

52. A pure substance or tested mixture falls into Subdivision A of Division 2 of Class D — Poisonous and Infectious Material if, in an animal assay for chronic toxic effects, it elicits a response of sufficient severity to threaten life or cause serious permanent impairment in a statistically significant proportion of the test population at

  • (a) a dose not exceeding 10 milligrams per kilogram of body weight of the animal per day when tested in accordance with

    • (i) OECD Test Guideline No. 408, “Subchronic Oral Toxicity — Rodent: 90-day”, dated May 12, 1981,

    • (ii) OECD Test Guideline No. 409, “Subchronic Oral Toxicity — Non-Rodent: 90-day”, dated May 12, 1981, or

    • (iii) the oral route test in OECD Test Guideline No. 452, “Chronic Toxicity Studies”, dated May 12, 1981;

  • (b) a dose not exceeding 20 milligrams per kilogram of body weight of the animal per day when tested in accordance with

    • (i) OECD Test Guideline No. 411, “Subchronic Dermal Toxicity: 90-day”, dated May 12, 1981, or

    • (ii) the dermal route test in OECD Test Guideline No. 452, “Chronic Toxicity Studies”, dated May 12, 1981; or

  • (c) a concentration not exceeding 25 parts per million by volume of gas or vapour, or not exceeding 10 micrograms per litre or 10 milligrams per cubic metre of dust, mist or fume when tested in accordance with

    • (i) OECD Test Guideline No. 413, “Subchronic Inhalation Toxicity: 90-day”, dated May 12, 1981, or

    • (ii) the inhalation route test in OECD Test Guideline No. 452, “Chronic Toxicity Studies”, dated May 12, 1981.

Teratogenicity and Embryotoxicity

  • 53. (1) A pure substance or tested mixture falls into Subdivision A of Division 2 of Class D — Poisonous and Infectious Material if, in an animal assay for teratogenicity and embryotoxicity, it is shown to cause injury to the embryo or fetus in a statistically significant proportion of the test population at a concentration that has no adverse effect on the pregnant female when tested in accordance with

    • (a) OECD Test Guideline No. 414, “Teratogenicity”, dated May 12, 1981;

    • (b) OECD Test Guideline No. 415, “One-Generation Reproduction Toxicity”, dated May 26, 1983; or

    • (c) OECD Test Guideline No. 416, “Two-Generation Reproduction Toxicity”, dated May 26, 1983.

  • (2) In this section, “injury” includes death, malformation, permanent metabolic or physiological disfunction, growth retardation or psychological or behavioural alteration that occurs during pregnancy, at birth or in the postnatal period.