Food and Drug Regulations

C.04.416 (1) The maximum quantity of whole blood that may be collected by plasmapheresis from a donor at one time is

• (a) where the donor’s weight is 40 kg or more but not more than 50 kg, 9 mL per kg of body weight;

• (b) where the donor’s weight is more than 50 kg but not more than 80 kg, 500 mL; or

• (c) where the donor’s weight is more than 80 kg, 600 mL.

(2) The maximum feasible volume of red blood cell suspension shall be returned to a donor before another unit of whole blood is collected from him.

(3) If the red blood cell suspension of the first collection of whole blood cannot be returned to the donor, then no further collection of blood shall be made for three months.

(4) No more than two donations of plasma shall be collected from a donor within any 48-hour period.

(5) No more than four donations of plasma shall be collected from a donor within any seven-day period.

(6) The maximum quantity of whole blood, not including anticoagulant, that may be collected by plasmapheresis from a donor within any six-month period is

• (a) where the donor’s weight is less than 50 kg, 19 L;

• (b) where the donor’s weight is 50 kg or more but not more than 80 kg, 26 L;

• (c) where the donor’s weight is more than 80 kg, 31 L.