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Hazardous Products Regulations

Version of section 8.5 from 2022-12-15 to 2024-04-01:


Marginal note:Definitions

 The following definitions apply in this Subpart.

genotoxicity

genotoxicity means the alteration of the structure, information content or segregation of DNA by an agent or process, including those agents or processes that cause DNA damage by interfering with normal replication processes or that in a non-physiological manner temporarily alter its replication. (génotoxicité)

germ cell mutagen

germ cell mutagen means a mixture or substance that is liable to lead to an increased occurrence of mutations in the germ cells of a population. (mutagène des cellules germinales)

germ cell mutagenicity

germ cell mutagenicity means an increased occurrence of heritable gene mutations, including heritable structural and numerical chromosome aberrations in germ cells, occurring after exposure to a mixture or substance. (mutagénicité sur les cellules germinales)

mutagenic

mutagenic means, in relation to a mixture or substance, liable to lead to an increased occurrence of mutations in populations of cells or organisms. (mutagène)

mutagenicity

mutagenicity means an increased occurrence of mutations in populations of cells or organisms. (mutagénicité)

mutation

mutation means a permanent change in the amount or structure of the genetic material in a cell and includes

  • (a) the heritable genetic changes that may be manifested at the phenotypic level; and

  • (b) the underlying DNA modifications when known, including specific base pair changes and chromosomal translocations. (mutation)

  • SOR/2022-272, s. 47

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