Controlled Substances Regulations (SOR/2025-242)

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Regulations are current to 2026-03-17

The following schedule is not in force.

SCHEDULE 4(Subsections 1(1) and 6(1) and (2), paragraphs 11(1)(f), 12(1)(c) and (i), 34(1)(h), 39(d), 42(1)(h), 47(d), 56(d), 61(d), 62(d) and 69(1)(d), subparagraph 72(e)(iv), paragraphs 73(1)(g), 75(d), 76(d), 77(a), 78(b), 80(g), 81(d), 82(d), 83(b), 84(e), 85(1)(a), 128(2)(d), 129(d), 141(c), 142(d), 143(2)(e), 146(f) and 147(f), section 198, paragraphs 205(1)(g), 210(d), 213(1)(g), 218(d) and 229(1)(c) and item 1 of Part 1 of Schedule 2)Restricted Drugs

PART 1

Item	Name
1	The following amphetamines, their salts, derivatives, isomers and analogues and salts of derivatives, isomers and analogues: (1) N-ethylamphetamine (N-ethyl-alpha-methylbenzeneethanamine) (2) 4-methyl-2,5-dimethoxyamphetamine (STP) (2,5-dimethoxy-4,alpha-dimethylbenzeneethanamine) (3) 3,4-methylenedioxyamphetamine (MDA) (alpha-methyl-1,3-benzodioxole-5-ethanamine) (4) 2,5-dimethoxyamphetamine (2,5-dimethoxy-alpha-methylbenzeneethanamine) (5) 4-methoxyamphetamine (4-methoxy-alpha-methylbenzeneethanamine) (6) 2,4,5-trimethoxyamphetamine (2,4,5-trimethoxy-alpha-methylbenzeneethanamine) (7) N-methyl-3,4-methylenedioxyamphetamine (MDMA) (N,alpha-dimethyl-1,3-benzodioxole-5-ethanamine) (8) 4-ethoxy-2,5-dimethoxyamphetamine (4-ethoxy-2,5-dimethoxy-alpha-methylbenzeneethanamine) (9) 5-methoxy-3,4-methylenedioxyamphetamine (7-methoxy-alpha-methyl-1,3-benzodioxole-5-ethanamine) (10) N,N-dimethyl-3,4-methylenedioxyamphetamine (N,N,alpha-trimethyl-1,3-benzodioxole-5-ethanamine) (11) N-ethyl-3,4-methylenedioxyamphetamine (N-ethyl-alpha-methyl-1,3-benzodioxole-5-ethanamine) (12) 4-ethyl-2,5-dimethoxyamphetamine (DOET) (4-ethyl-2,5-dimethoxy-alpha-methylbenzeneethanamine) (13) 4-bromo-2,5-dimethoxyamphetamine (4-bromo-2,5-dimethoxy-alpha-methylbenzeneethanamine) (14) 4-chloro-2,5-dimethoxyamphetamine (4-chloro-2,5-dimethoxy-alpha-methylbenzeneethanamine) (15) 4-ethoxyamphetamine (4-ethoxy-alpha-methyl-benzeneethanamine) (16) N-Propyl-3,4-methylenedioxyamphetamine (alpha-methyl-N-propyl-1,3-benzodioxole-5-ethanamine) (17) N-hydroxy-3,4-methylenedioxyamphetamine (N-[alpha-methyl-3,4-(methylenedioxy)phenethyl]hydroxylamine) (18) 3,4,5-trimethoxyamphetamine (3,4,5-trimethoxy-alpha-methylbenzeneethanamine)
2	Lysergic acid diethylamide (LSD) (N,N-diethyllysergamide) and its salts
3	N,N-Diethyltryptamine (DET) (3-[(2-diethylamino)ethyl]indole) and its salts
4	N,N-Dimethyltryptamine (DMT) (3-[(2-dimethylamino)ethyl]indole) and its salts
5	N-Methyl-3-piperidyl benzilate (LBJ) (3-[(hydroxydiphenylacetyl)oxy]-1-methylpiperidine) and its salts
6	Harmaline (4,9-dihydro-7-methoxy-1-methyl-3H-pyrido(3,4-b)indole) and its salts
7	Harmalol (4,9-dihydro-1-methyl-3H-pyrido(3,4-b)indol-7-ol) and its salts
8	Psilocin (3-[2-(dimethylamino)ethyl]-4-hydroxyindole) and its salts
9	Psilocybin (3-[2-(dimethylamino)ethyl]-4-phosphoryloxyindole) and its salts
10	N-(1-phenylcyclohexyl)ethylamine (PCE) and its salts
11	1-[1-(2-Thienyl)cyclohexyl]piperidine (TCP) and its salts
12	1-Phenyl-N-propylcyclohexanamine and its salts
13	Mescaline (3,4,5-trimethoxybenzeneethanamine) and its salts, but not peyote (lophophora)
14	2-Methylamino-1-phenyl-1-propanone and its salts
15	1-[1-(Phenylmethyl)cyclohexyl]piperidine and its salts
16	1-[1-(4-Methylphenyl)cyclohexyl]piperidine and its salts
17	Etryptamine (3-(2-aminobutyl)indole) and its salts
18	Rolicyclidine (1-(1-phenylcyclohexyl)pyrrolidine) and its salts
19	Benzylpiperazine (BZP), namely 1-benzylpiperazine and its salts, isomers and salts of isomers
20	Trifluoromethylphenylpiperazine (TFMPP), namely 1-(3-trifluoromethylphenyl)piperazine and its salts, isomers and salts of isomers
21	Methylenedioxypyrovalerone (MDPV), its salts, derivatives, isomers and analogues and salts of derivatives, isomers and analogues
22	Cathinone ((-)-alpha-aminopropiophenone) and its salts
23	2C-phenethylamines and their salts, derivatives, isomers and salts of derivatives and isomers that correspond to the following chemical description: any substance that has a 1-amino-2-phenylethane structure substituted at the 2’ and 5’ or 2’ and 6’ positions of the benzene ring by an alkoxy or haloalkoxy group, or substituted at two adjacent carbon atoms of the benzene ring which results in the formation of a furan, dihydrofuran, pyran, dihydropyran or methylenedioxy group — whether or not further substituted on the benzene ring to any extent, whether or not substituted at the amino group by one or two, or a combination of, methyl, ethyl, propyl, isopropyl, hydroxyl, benzyl (or benzyl substituted to any extent) or benzylene (or benzylene substituted to any extent) groups and whether or not substituted at the 2-ethyl (beta carbon) position by a hydroxyl, oxo or alkoxy group — and its salts and derivatives and salts of derivatives, including (1) 4-bromo-2,5-dimethoxy-N-(2-methoxybenzyl)phenethylamine (25B-NBOMe) (2) 4-chloro-2,5-dimethoxy-N-(2-methoxybenzyl)phenethylamine (25C-NBOMe) (3) 4-iodo-2,5-dimethoxy-N-(2-methoxybenzyl)phenethylamine (25I-NBOMe) (4) 4-bromo-2,5-dimethoxybenzeneethanamine (2C-B)
24	AH-7921 (1-(3,4-dichlorobenzamidomethyl)cyclohexyldimethylamine), its salts, isomers and salts of isomers
25	MT-45 (1-cyclohexyl-4-(1,2-diphenylethyl)piperazine), its salts, derivatives, isomers and analogues and salts of derivatives, isomers and analogues, including (1) Diphenidine (DEP) (1-(1,2-diphenylethyl)piperidine) (2) Methoxphenidine (2-MeO-Diphenidine, MXP) (1-[1-(2-methoxyphenyl)-2-phenylethyl]piperidine) (3) Ephenidine (NEDPA, EPE) (N-ethyl-1,2-diphenylethylamine) (4) Isophenidine (NPDPA) (N-isopropyl-1,2-diphenylethylamine) but not including (5) Lefetamine ((-)-N,N-dimethyl-alpha-phenylbenzeneethanamine), its salts, derivatives and isomers and salts of derivatives and isomers
26	W-18 (4-chloro-N-[1-[2-(4-nitrophenyl)ethyl]-2-piperidinylidene]benzenesulfonamide), its salts, derivatives, isomers and analogues and salts of derivatives, isomers and analogues
27	U-47700 (3,4-dichloro-N-(2-(dimethylamino)cyclohexyl)-N-methylbenzamide), its salts, derivatives, isomers and analogues and salts of derivatives, isomers and analogues, including (1) Bromadoline (4-bromo-N-(2-(dimethylamino)cyclohexyl)benzamide) (2) U-47109 (3,4-dichloro-N-(2-(dimethylamino)cyclohexyl)benzamide) (3) U-48520 (4-chloro-N-(2-(dimethylamino)cyclohexyl)-N-methylbenzamide) (4) U-50211 (N-(2-(dimethylamino)cyclohexyl)-4-hydroxy-N-methylbenzamide) (5) U-77891 (3,4-dibromo-N-methyl-N-(1-methyl-1-azaspiro[4.5]decan-6-yl)benzamide)

PART 2

Item	Name
1	Salvia divinorum (S. divinorum), its preparations and derivatives, including (1) Salvinorin A ((2S,4aR,6aR,7R,9S,10aS,10bR)-9-(acetyloxy)-2-(3-furanyl)dodecahydro-6a,10b-dimethyl-4,10-dioxo-2H-naphtho[2,1-c]pyran-7-carboxylic acid methyl ester)
2	Catha edulis Forsk, its preparations, derivatives, alkaloids and salts, including (1) Cathine (d-threo-2-amino-1-hydroxy-1-phenylpropane) but not including (2) Cathinone ((-)-alpha-aminopropiophenone) and its salts

PART 3

Item	Column 1	Column 2
Item	Substance	Period

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Date modified:: 2026-04-01

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Controlled Substances Regulations (SOR/2025-242)

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